Mind Over Matter

Use Public Sympathy, Origami and Duggar's to fill your hand to monstrous proportions. Off the bat, this should keep you safe from damage of any kind.

Then, with Ekomind installed, get an Overmind out with a ridiculous counter count.

Now make Interface-enabled runs. Use Stimhack to boost Overmind's strength for free, and proceed to break subroutines for free with counters.

For especially big ICE, use D4v1d. For Swordsman, use Mimic. For double Wraparound use Corroder. Duggar's should help you obtain these 1-ofs.

Replay Stimhacks using SOS and reset your Overmind's counters (and D4v1d if needed) using Scavenge.