Mrs. Merchant is very quickly shaping up to be my favourite runner identity. Here's why:

Hand Ob(or De-)struction is something most corps can't deal with. Her ability is a fruitful package of disruption and archives pressure. It's true, the discard isn't randomized, but considering that 1. It will often trigger early, when the corp has not had time to develop yet and 2. As the game progresses, you will often find the Corp without many cards in hand, making every discard painful.

In fact, the reason why I enjoy her playstyle so very much may stem from the fact that she bears certain similarities to my all-time favourite corp identity, Jinteki: Personal Evolution. Both warp the opponent's playstyle to a degree, by denying them cards they would usually have access to, thereby making their game plan unreliable (this is especially true forcombo decks). But whereas PE is reactive and relies on traps and forcing decisions, Alice is proactive and terrorizes the corporation at her own behest.

And running is where she's good at. Since you already have an in-built archives pressure, you will traditionally want for HQ and RnD threats, since Anarchs have a bit of a harder time entering remotes. Medium and Bhagat (Alice lends herself nicely to a resource-intensive build, so [[Career Fair]] is a solid pick), with additional cards that reward running centrals ([[Datasucker]] and [[Tapwrm]]) being rock-solid includes.

Overall, an incredible addition to the game and, as the poets say: "You can run the Jewels, or lose ya fingers."