Hokusai Grid is there for grinder deck. It fit perfectly with Jinteki Personal Evolution. And with a cost of 2 influences, it is easily used with other grinder like Builder of Nation.
In a pinch, it will punish runner for using Stargate, Diversion of Fund, Legwork, The Maker's Eye or Khusyuk. It does not stop them like Crisium Grid, but is cost zero influence inside Jinteki. Runners with the aforementionned cards will have to come back to trash the card, taking another net damage in the process. It work wonders in NBN Controlling the Message, because it become a must trash card, thus triggering the ID.
With a cost of 2 and a trash cost of 4, it bring in a good credit differential, along with the pain of 1 net damage. The only drawback is the region effect. Which mean it cannot be paired with other popular region like Crisium Grid or Jinja City Grid.
This upgrade will make any run painful, no matter for what. With Chronos Protocol, it is an absolute beast of a card, allowing the corp to trash the best card in hand.
Outside Jinteki, you might prefers Prisec. But inside Jinteki, Hokusai is very good.