If the runner encounter it 3 times or less, Wall of Static is a better choice. So, obviously, you'll want this one where the runner will run (very) often.

It can be viable protecting archive against any deck with Datasucker or on centrals in Jinteki: Replicating Perfection, but not on periphery since the runner will just bounce on the ERT routine (after Pup or Komainu maybe?)

Personally, I use it in Jinteki: Replicating Perfection to protect my economy assets (Sundew, Mental Health Clinic, PAD Campaign and Melange Mining Corp.). Every time the runner runs it to trash my Sundew (and you know he will) it's become more and more expansive.

So the key thing you need to ask yourself when you are deciding whether this is the ice for your deck is "how many times do I expect the runner to break this?" and "Where would I install this?".

After being broken 5 times, Quicksand costs 1 credit more than Wall of Static would have, at 11 to 10

After being broken 9 times, Quicksand costs 1 credit more than Eli 1.0 would have, at 37 to 36

(The costs above were determined for breaking with Corroder)

Of course, where this should be installed is also an interesting question, the most obvious answer is R&D if you tend to lose due to R&D Lock, or to a lesser extent R&D Digging, but it may also be good installed elsewhere, for example, against Gabe it may be a very good idea to plant one of these on HQ, and archives to make his Sneakdoor Shenanigans less effective.

The other thing is that if you can somehow cause the runner to encounter Quicksand more than once per run (Cough Mumbad Cough) then Quicksand could become very taxing very quickly, Assuming it doesn't get Parasited or Knifed immediately of course, and Quetzal just laughs in it's face.

I always love to see power counter cards, because I feel like we need a few more to make the strategy viable. This card may have a place when paired with Helium-3 Deposit, IT Department, and Data Raven. You could also include Snoop or Viktor 2.0, but it's probably not a good idea to put too many eggs into the power counter basket just yet.