Can't help but feel like Degree Mill's defensive protection isn't as strong as it seems. The main problem is that the Runner gets to decide which cards to shuffle back. Best-case scenario, you force the runner into shuffling back the first few things they installed (a console or Mopus perhaps) to prevent you from being at game-point. But the expected case will often be runners sending back SacCons, extra Rabbit Holes, even Tapwrm. And it can get even worse when a runner shuffles back a depleted Armitage, Liberated, D4v1d, etc. to be installed and re-used again.
I agree that this 5/3 is excellent when scored in the early game but it definitely weakens as the game goes on. Yes, it's nigh unstealable turn 1 but are you really going to IAA it and leave your centrals open? This has a place, for sure, in NBN rush decks like what we can expect from the new Azmari EdTech. Overall though, I think Global Food Initiative reigns supreme as the better defensive option and SSL Endorsement for a more consistent tempo swing.