One of the biggest advantages that runners have is their ability to use their heap. Criminals love using Same Old Thing to stretch their Account Siphons, Shapers love Clone Chipping their Ladies, and Anarchs love pulling back those juicy viruses with Déjà Vu. The runners most notorious for this are, of course, Exile and MaxX, but almost every deck these days runs some form of recursion.
Chronos Project shuts all this down hard and fast. No, you may not recur those Parasites. No, you may not Levy AR Lab Access to get back all your economy events. No, you may not Scavenge to swap your Cyber-Cyphers. No, you may not Same Old Thing that Legwork. No, no, no, no, no.
This gets even nastier in a deck that trashes cards, either through destroyers like Grim or net damage like Blacktree's Thousand Cuts archetype. Oh, I'm sorry, all of your Corroders were in the garbage? Well, I just took out the trash.
This card ranges from "mildly annoying" to "absolutely game-ending", depending on the matchup and when it gets scored. If you can afford to lower your agenda density with a 3/1, this is strong option.