Used all three of your Biotics? Take it back in hand when you have a 3/2 in hand for the win.
Must trash for almost all runners... and that's the problem. Technically, we should compare this to a reoccuring Archived Memories. But we can't take back our more important stuff like Ash or Nisei with it, and it does cost 1, although ETF does give you that credit back I guess. It's a tossup: would you like to waste a runner click making them trash this and not being able to take back things that arn't operations, or would you prefer just playing an Archived Memories from hand?
If you're playing sideways decks, this can be useful to grab Hedge Fund again and again until they go to trash it, but other than that, you're probably wanting a Archived Memories.