Study Guide is an interesting breaker that can ramp up as the game progresses, in theory. A corp will typically start by installing cheap ice until its economy can support something more expensive. This means you can throw down Study Guide and increase its strength as needed. Rielle "Kit" Peddler: Transhuman no longer has to decide between Torch and ZU.13 Key Master or Gordian Blade
In practice this isn't the case. Some of the most common early ICE are Enigma and Eli 1.0. Who wants to pay 9 credits to install and break Enigma. 13 for Eli? No thanks! Even if Study Guide is beefed up for the rest of the game, that credit hit opens a scoring window the next turn.
That being said, in combo with Personal Workshop and Stimhack, Kit can really make it shine. So is it worth one brain damage to install and boost Study Guide's strength to strength 3? I think so, if you're running Plascrete Carapace.