When I first saw Clyde Van Rite, I thought he would be a great fit for Jinteki prison decks. Jinteki: Potential Unleashed + Hostile Infrastructure + Bio-Ethics Association + Clyde Van Rite = lose 1 credit and 2 cards each turn (minimum), or lose 3 cards, Runner's choice. Throw a Scarcity of Resources or Housekeeping on top of that, and you're potentially creating a huge tempo hit.
However, that's a lot of influence for an ID with only 12 influence to spend. Where else might Mr. Van Rite shine? How about Spark Agency: Worldswide Reach? Spark Agency: Worldswide Reach + any advertisement that can rezzed at the beginning of the Corp's turn + Clyde Van Rite + Bryan Stinson = lose 1-2 or 1 and a card, and if that 1-2 loss puts you below 6, I play a transaction on my first click from archives. Considering all of the cards NBN has in-faction to drain the Runner of credits, NBN may be Mr. Van Rite's "home away from home."
I struggle to think of how well Weyland will make use of him. Gagarin Deep Space: Expanding the Horizon + Crisium Grid + Off the Grid + Clyde Van Rite = the runner loses 1 or a card, and then on their turn has to spend at least 2 s to run HQ, trash Crisium, then run Clyde's server. I'm not going to calculate the cost, becuase that's infinitely variable, however, throw Service Outage or Enhanced Login Protocol on top of that to make the runs even harder.
I'm struggling even harder to see how HB might use this card, so I'll leave that to the rest of you.
On his own, Clyde Van Rite probably isn't the strongest of cards. 2 rez, 3 trash puts it right in range of Whizzard: Master Gamer, Scrubber, and Paricia - all favored hate cards. Perhaps this is a good thing. Will the runner spend their and recurring s to trash Clyde when there may be better choices for them to make? Could that spent and s create a small tempo hit and a window from which the Corp can score? Of course the card is countered out right by Rumor Mill, Hacktivist Meeting, Political Operative, Drive By, and Councilman; many cards are vulnerable to these cards and always have been and always will be - counter play is intentional.
Cards don't exist in a vacuum, and other than acting as bait for wasting the Runner's s and s, Clyde Van Rite can be setup as a trap with various upgrades: Prisec, Hokusai Grid, and Mumbad Virtual Tour to name a few. ICE of course always adds a layer of the unknown.
In the end, only thorough play-testing will reveal just how good, or bad Clyde Van Rite may be, and where he truly shines and loses. I can't wait to see how he's used.