Rime is almost a staple in every one of my corp decks now because of how painful it can be. The only times I can't use it are when I get DDoS'd. First, it's a tax: unless an AI is on the field (like my favorite turtle) or a transhumanist, the Runner is always losing money on a Rime server run. Not just from Rime, mind you. All of a sudden, any ice in that server becomes far more dangerous. Archer goes to a strength 7, Fairchild is expensive as all hell to break, Hydra gains an additional head (so to speak), and even Kakugo becomes that much more painful. Furthermore, ice with abilities relying on other ice (like Seidr Adaptive Barrier and Surveyor) benefit from the +1 strength.
One last detail to mention... RIME IS NOT UNIQUE. You can have all three out at once and rezzed, making each of your servers a bit harder to get through, or stack three on top of a particularly painful piece of ice to make it even more spectacularly painful. Did I mention it costs absolutely no influence? Why are you not running Rime? The only reason I can think you wouldn't run it is because you're playing Runner at the moment.
Well, the only problem it's that it's a porous Ice and you may want to keep pace, so maybe for that a vanilla could be better. Or maybe you don't rely on towers of ice.
— valerian32