Don't let that 'T' in the background fool you--Bryan has his offices at Titan, but he's a GRNDL man through and through. Yes, there's a lot of fancy tricks involving various cards with 'Account' in their name, or you can try taxing out the runner and hoping you can get them below 6 credits so that Bryan can work his magic. But that eats deck space, and more importantly takes time. But you get one turn in every game where Bryan Stinson is 100% guaranteed to be able to work his financial magic--your very first turn of the game. You can play a transaction, play Bryan, and then replay your transaction, and say go. It stands to reason, then, that you want to make that turn as big as possible.
Enter GRNDL. While most corps have to settle for Hedge Fund, bringing them up to a 'mere' 17 credits (or 19 in the case of Building a Better World), GRNDL starts with enough credits to immediately Restructure, which becomes truly absurd with Bryan Stinson, catapulting you to 28 credits on turn one. That is a LUDICROUS pile of money that that the runner cannot hope to match--even the powerful Temüjin Contract is only going to get them to 21, and that's if they do nothing but install it and run. The best the runner can do is double Account Siphon, in which case they have made a conscious decision to float tags against GRNDL, and what happens next is just going to improve the average IQ of New Angeles residents.
Now that you are filthy stinkin' rich, the runner is trapped, even though you have no board to speak of, because the spectre of being Midseasoned for roughly infinity looms large over them. You can install a naked agenda, turn it face up to show the runner that this is indeed an agenda and not a trap, double advance it and ship turn, and the runner will have no choice but to let you score it (which, this being GRNDL, is probably just going to result in you getting even richer). They can run Stinson, but unless they're Whizzard, trashing him is just going to put them even further behind economically, and you'll be able to comfortably maintain your lead the old-fashioned way. And if they try to build up their rig, they either have to stay above 5 credits and watch you score out as they set up, or they can concede that your bank account statement is just going to read"Yes", and that they will be nailed the instant they steal points.
This plan isn't foolproof--it requires you to have Stinson and a good transaction in your opener, Film Critic continues to exist, and if the deck stacks against you and you don't see your kill cards. But that's all going to feel very distant indeed when you're busy buying the entire Cayman Islands.