If you're trying to score 3/2s out of hand, SanSan City Grid is a lot more economically efficient. Vlad Grid makes it somewhat safer to score 4/2s out of hand, but the added install click and rez cost feels unwieldy for what it offers. 2 counters invested is a major commitment and most runners will trash it there. If you're looking for an advanceable semi-trap to bait runs, I guess it's okay. With NGO Front, you hope they check, with Vlad Grid, you're probably hoping they don't. Problem: against NBN they usually do.
I don't anticipate a lot of use for this card for fast-advance while SanSan is available; if your gameplan calls for scoring cards out of hand, 3/2s are much more reliable than 4/2s. With SanSan, you can score a 3/2 every turn. With Vlad City, you can score a 4/2 every two turns. You have to love your 4/2 effects for that to be worth building around. You also have to be SO tight on influence that the cheaper/safer Seamless Launch doesn't work.
If you have enough influence for Dedication Ceremony, but not for Reconstruction Contract, this might be a viable ReCo alternative for NBN players who care more about influence or reusability than efficency. Suppose you end a turn with a Vlad City Grid lurking on the board. Next turn, you could use Dedication Ceremony and score a 3/2. This leaves your Vlad City with one token on it, which allows you to threaten another 3/2 next turn. (Install agenda, advance the agenda, place a second token on Vlad City, and then move 2 tokens from Vlad City).
Vlad City might create options for other advanceable cards. If you have a Reversed Account (and no influence for Dedication Ceremony), it will probably spend at least one turn on the board with 1+ counter on it. (Very few people install a RA, advance it once, and then trigger it that turn, that's probably not the play). However, if Vlad City feeds your Reversed Account 2 counters, triggering a Reversed Account on the turn it is installed would be stronger. Problem: a Vlad City left on the board with 2 counters is even less likely to survive the turn than a Reversed Account with 1. Another problem is that Dedication Ceremony is so much more efficient than Vlad City for most advanceable assets.
Vlad City might create janky fun for Improved Protein Source or any cards you wanted to play on top of an agenda score. 4 influence for a not very good card is rough, but if you're playing Improved Protein Source, you probably aren't playing for power.