Aggressive Secretary is a form of rig shooting. Here is a small trick : put it on the board with a single advance, because runner are less afraid of single advance than double advance (especially if it is on the board without protection).
Aggresive Secretary pair well with Blacklist (program cannot be brought back) and Ark Lockdown (program are taken out of the game). If you like, you can also pair it with Hangeki, to pressure the runner into taken the trap, else they take a negative point agenda.
Simulchip (the descendant of Clone Chip) will protect the runner from Aggressive Secretary. Heap breakers will not care too much about it.
Where Project Junebug and Cerebral Overwriter aim to damage the runner and set them up for kill, Aggressive Secretary aim to disrupt the runner. Either it will cost credits (to reinstall program) and tempo (finding that program) or making runs more difficult (not having the breaker mean taking the penalties of the subs). In this, it can be compared to Neurostasis.
Of note, you can use Back Channel to get 3 creds per advancement token on Aggressive Secretary. So, if the runner does not run it, you can make a nice amount of creds. But it is inefficient (just slightly better than clicking for credits).
Every faction have disruption traps. Jinteki has Neurostasis, Weyland as False Flag and NBN as Ghost Branch. Aggressive Secretary is the weakess of all of them, since it is specialized. Early, when there is no program on the board, it does nothing. This is why there is not much reason to include this trap in deck from other factions.
Even for the rig shooter archetype, which aim to lock the runner from running by trashing their breakers (or at least, disrupt the runner), you will be better off using cards like Keegan Lane, Trojan Horse or Marcus Batty.
The art is nice and evocative, even if I would have prefered a Bioroid themed secretary. Suggested quote : "I'll be confiscating that, thank you".